Evidence-appraisal glossary

Confidence interval

A confidence interval is a range of values, computed from data, that is likely to contain the true effect. A 95 percent interval means that if the study were repeated many times, about 95 percent of such intervals would capture the real value. Its width reflects the precision of the estimate.

Also called: CI, 95% CI.

A confidence interval gives a range of plausible values for an effect, rather than a single point estimate, and conveys how precise that estimate is. A narrow interval signals a precise result; a wide one signals uncertainty, often from a small sample. The standard interpretation is about the procedure: across many repeated studies, 95 percent of the intervals produced would contain the true value. When reading a study, look at the whole interval, not just the point estimate. Check whether it crosses the value of no effect (zero for a difference, one for a ratio), which signals the result is compatible with no effect, and check whether both ends would be practically meaningful. For example, a drug reported to cut risk by 30 percent with a 95 percent interval of 5 percent to 50 percent shows a benefit that could be modest or large, whereas an interval of 28 percent to 32 percent would be far more precise. Wide intervals warn against over-reading a headline number.

This is a plain-language methodology definition for reading research. It is general education, not medical advice.

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